What Do You Know About Xarelto?

Many medications can increase your risk of bleeding when used along with Xarelto. This is why your doctor should know your medical history and the treatments you're undergoing or have recently undergone.
What Do You Know About Xarelto?

Last update: 03 June, 2021

Xarelto is a medication made up of an active substance called rivaroxaban. It’s an anticoagulant used to treat or prevent blood clots in the legs, lungs, and brain.

These types of clots can form due to various circumstances. After knee or hip surgery and during or after being in the hospital for a while and you can’t move normally, for example.

Indications for Xarelto

A burst vein.
This drug is a licensed oral anticoagulant to prevent stroke and systemic embolism.

Indications for Xarelto include:

  • The drug is intended to reduce the risk of a blood clot re-forming after being under treatment with anticoagulants for at least 6 months. Xarelto is also prescribed to reduce the risk of cerebrovascular incidents in people with atrial disorders.
  • People are to take it in combination with aspirin to reduce their risk of cerebrovascular incidents.
  • Stroke prevention.

Rivaroxaban has notable side effects though. For one, it can cause bleeding and subsequent hemorrhages. Especially if you have any of these conditions:

  • A hereditary bleeding disorder
  • A hemorrhagic stroke
  • Uncontrolled high blood pressure
  • Bleeding or ulcer of the stomach or intestine

Important information about Xarelto

Don’t stop treatment with this drug without discussing it with your doctor first. This is because doing so abruptly will significantly increase the risk of blood clots or a stroke.

Also, talk to your doctor if you experience signs of bleeding when you’re taking Xarelto, such as the following:

  • Bleeding gums
  • Nosebleeds
  • Heavy menstrual periods
  • Abnormal vaginal bleeding
  • Blood in urine and stools
  • Bloody cough
  • Bloody vomiting that looks like coffee grounds

Many medication interactions with Xarelto increase your risk of bleeding. For this reason, your doctor needs to be aware of any treatments you’re either undergoing or have recently undergone.

In addition, don’t start treatment with Xarelto if you’re allergic to its active substance, or if you have active or uncontrolled bleeding when you’re about to begin treatment with it.

How should I take rivaroxaban?

A person with a headache.

The maximum recommended dose is 20 mg per day. Rivaroxaban (xarelto) is rapidly absorbed, reaching its peak levels two to four hours after taking it. Furthermore, the effect of this drug increases if you take it with a meal. Also, its absorption increases by up to 39% compared to that obtained by taking the drug on an empty stomach.

However, it may be necessary to make changes in successive doses, even though the recommended dose is one 20 mg tablet per day. Thus, as mentioned above, you shouldn’t stop treatment suddenly as it would increase the risk of blood clots or a stroke.

In case you have to undergo surgery while taking this medication, you must inform the surgeon that you’re undergoing treatment. This is so they can take the appropriate measures.

What are the side effects of rivaroxaban?

The adverse reactions reported in studies with rivaroxaban include:

  • Frequent side effects: bleeding, anemia, dizziness, headache, tachycardia, low blood pressure, leg and arm pain, fever, fatigue, and tiredness
  • Less frequent side effects: thrombocytopenia, allergic reactions, dry mouth, renal failure, general malaise, alterations of different analytical parameters
  • Rare side effects: jaundice

Seek medical attention if you experience symptoms of an allergic reaction such as difficulty in breathing, swelling of the face, lips, tongue, or throat.

In addition, consult your doctor if you experience symptoms of clotting in the spinal cord. For instance, back pain, muscle weakness in the lower body, or loss of bladder control are some of the most common ones.

Conclusion

Finally, Xarelto is an oral anticoagulant prescribed for the prevention of stroke and embolism. Especially in patients with some types of atrial fibrillation who also have one or more risk factors.

This drug can cause serious side effects if misused, so you must follow a specialist’s instructions at all times.

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Recommendations for People on Anticoagulant Treatment
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Recommendations for People on Anticoagulant Treatment

Anticoagulant treatment, as its name clearly states , is used to prevent the blood from carrying out the clotting process.



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  • Kirchhof, P., Radaideh, G., Kim, Y. H., Lanas, F., Haas, S., Amarenco, P., … Camm, A. J. (2018). Global Prospective Safety Analysis of Rivaroxaban. Journal of the American College of Cardiology. https://doi.org/10.1016/j.jacc.2018.04.058